EpiCor® Postbiotic Now Offering Immune Support to Food & Beverage Industry

The U.S. Food and Drug Administration (FDA) responded with a letter of no objection to Cargill’s GRAS (Generally Recognized As Safe) notification for EpiCor^® postbiotic use in certain foods and beverages.

EpiCor^® postbiotic is a dried yeast fermentate clinically shown in dietary supplement trials to beneficially modulate the gut microbiota and provide immune system support. A first-of-its-kind postbiotic widely used in popular supplements, the letter of no objection enables food and beverage manufacturers to incorporate EpiCor^® into a variety of foods and beverages.

“Increasingly, consumers are seeking food and beverages that offer better ways to support their health,” said Chuck Warta, president, Cargill Health Technologies. “Through our work in understanding and influencing the microbiome, Cargill is creating solutions like EpiCor^® postbiotic that support digestive and immune health at all stages of life and help both people and pets live more healthy days.”

Postbiotics are an emerging category in the immune and gut health space. Earlier this month, the International Scientific Association for Probiotics and Prebiotics (ISAPP) published a consensus statement on the definition and scope of postbiotics in the Nature Reviews Gastroenterology & Hepatology journal. This consensus definition states postbiotics are “a preparation of inanimate microorganisms and/or their components that confer health benefits on the host.”¹

“This definition validates EpiCor^® as a postbiotic. Having an internationally recognized definition is an important step in broadly bringing the benefits of postbiotics to consumers,” said Liz Spence, general manager for EpiCor^®. “As a leader in postbiotic technology, we are continually investing in research and innovation and EpiCor^® postbiotic’s GRAS status helps to further demonstrate the safety of this platform.”

EpiCor^® postbiotic is backed by extensive research in dietary supplements. Fifteen published studies, including eight human clinical trials, support EpiCor^® postbiotic’s health benefits related to both digestive and immune support.

Beyond its researched health benefits, product developers will appreciate its ease of use. Because a postbiotic is not a live organism, it is highly heat stable and can handle varying pH levels. 

Adding to its appeal, Cargill recently received Non-GMO Project Verification for EpiCor^® postbiotic. “For brands looking to position their offerings in today’s health-conscious environment, EpiCor^® postbiotic has much to offer,” said Spence. “Its Non-GMO Project Verification adds another layer of credibility to a trusted product, with clinically shown immune and digestive health benefits in dietary supplements.”

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¹ Salminen, S., Collado, M.C., Endo, A. et al. The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nat Rev Gastroenterol Hepatol (2021). [https://www.nature.com/articles/s41575-021-00440-6]

About Cargill
Cargill’s 155,000 employees across 70 countries work relentlessly to achieve our purpose of nourishing the world in a safe, responsible and sustainable way. Every day, we connect farmers with markets, customers with ingredients, and people and animals with the food they need to thrive.

We combine 155 years of experience with new technologies and insights to serve as a trusted partner for food, agriculture, financial and industrial customers in more than 125 countries. Side-by-side, we are building a stronger, sustainable future for agriculture. For more information, visit Cargill.com 

About EpiCor^® Postbiotic
Backed by over a dozen published studies, EpiCor^® postbiotic has been clinically shown to support immune and gut health when taken as a dietary supplement. It is a one-of-a-kind whole food fermentate made through a specialized fermentation process that creates a unique fingerprint of metabolites. Inspired by a real-life health discovery and supported by award-winning science, EpiCor^® postbiotic helps people live more healthy days.TM For more information, visit www.epicoringredient.com